Apigenin 7-glucoside（578-74-5）

Apigenin-7-glucoside, also commonly known as Cosmosiin, with CAS number 578-74-5 and molecular formula C21H20O10, is a natural flavonoid glycoside compound and a critical water-soluble derivative of apigenin. Widely found in a variety of medicinal herbs and plants such as Pogostemon cablin, Agrimonia pilosa, chrysanthemum, motherwort and mulberry leaves, it is an essential secondary metabolite of plants. It plays a vital role in plant stress resistance and immune regulation, and possesses outstanding research significance and practical application value in modern medicine and health industry.

This product appears as pale yellow crystalline powder or acicular crystal with mild odor and no irritation. It has slight hygroscopicity and stable overall physicochemical properties. Compared with pure apigenin, the glucoside structure greatly improves its water solubility and biological absorption rate, overcoming the poor solubility and low bioavailability of common flavonoid ingredients. Although stable at room temperature, it is susceptible to oxidation and decomposition under strong light, high temperature and humid environment. Therefore, it should be stored in a sealed, light-proof, dry and low-temperature environment to maintain stable content and activity. It is slightly soluble in ethanol and methanol, and easily dissolved in DMSO, which meets the preparation requirements of pharmaceutical experiments, cosmetic formulation and industrial processing.

Cosmosiin is endowed with a variety of excellent biological activities, mainly including antioxidant, anti-inflammatory, antibacterial, antiviral and anti-proliferation effects. As a powerful natural antioxidant, it can efficiently scavenge reactive oxygen free radicals in the body, reduce oxidative stress damage, prevent lipid peroxidation and protect normal cells from aging. It can significantly inhibit the excessive secretion of inflammatory mediators and block inflammatory response pathways, showing remarkable soothing and anti-inflammatory capacity. A large number of pharmacological studies have confirmed that Apigenin-7-glucoside can regulate the cell cycle, inhibit the abnormal proliferation of lesion cells and promote cell apoptosis. With low toxicity and high safety, it will not cause damage to normal human cells, making it a safe natural active monomer.

In terms of practical application, Apigenin-7-glucoside covers multiple fields including scientific research reagents, pharmaceutical intermediates, health supplements, cosmetic raw materials and natural food additives. In pharmaceutical research, it is widely used as a high-purity reference standard for qualitative and quantitative analysis of flavonoids, as well as a core lead compound for the development of anti-inflammatory, antiviral and anti-tumor new drugs. In the cosmetic industry, relying on its antioxidant, soothing and barrier-repairing effects, it is added into anti-aging essence, sensitive skin care products and calming lotions to improve dull skin, relieve redness and enhance skin resistance.

In the field of health food and dietary supplements, it serves as a natural functional additive for antioxidant and immune-supporting products. At present, mature production technologies including natural plant extraction, separation and biotransformation can stably supply high-purity Cosmosiin with stable quality and controllable cost. Benefiting from its unique glycoside structure, mild performance and diversified physiological activities, Apigenin-7-glucoside has become one of the most popular natural plant active ingredients.

With the rapid development of natural medicine, functional cosmetics and global health industries, the market demand for safe and efficient plant-derived active monomers continues to rise. As a high-value flavonoid glycoside, Cosmosiin will surely gain wider application and in-depth research in the future, presenting broad development prospects and stable market potential.