GinkgolideCK(39262-14-1)

1. Product Basic Information

Product Name: Ginsenoside CKCAS Number: 39262-14-1Molecular Formula: C₃₆H₆₂O₈Molecular Weight: 622.88Appearance: White to off-white powder or pale yellow powder, odorless, no visible impuritiesPurity Specifications: 50%, 70%, 98%, customizable on requestSolubility: Soluble in methanol, ethanol, dichloromethane and other organic solvents, with good stability and compatibilitySource: Produced from natural diol‑type ginsenosides through biotransformation and efficient purification; derived from Panax ginseng, Panax notoginseng and other Araliaceae plants. It is the final active metabolite of ginseng in the human body.

Ginsenoside CK is the key active component produced by intestinal flora metabolism after oral administration of ginseng. Unlike common ginsenosides such as Rg3, Rh2 and Rb1, Ginsenoside CK does not require secondary metabolism and can be directly absorbed and utilized by the human body. Therefore, it has higher bioavailability, stronger physiological activity and more stable efficacy. As one of the most important and valuable components in the rare ginsenoside family, Ginsenoside CK has become a key natural active substance widely used in medicine, health care, cosmetics and functional food industries worldwide.

2. Production Process and Quality Advantages

Shaanxi Cuikang Pharmaceutical Technology Co., Ltd. relies on a 2,700 ㎡ R&D center, a professional natural product separation and purification platform, UPLC‑Q‑TOF high‑resolution mass spectrometry and mature pilot‑scale and industrial production lines. We have established an advanced preparation system combining biotransformation + chromatographic separation, which maximizes the structural integrity of active molecules, avoids by‑products, and ensures high purity, high activity and high safety.

We implement a full‑process quality control system from raw material screening, biotransformation, separation and purification, content testing, microbial control to finished packaging. Every batch of Ginsenoside CK is tested for sensory indicators, purity, solubility, moisture, ash, heavy metals, microbial limits and aflatoxin to meet pharmaceutical, health food and cosmetic grade standards.

We can stably supply 100g‑level, kg‑level and ton‑scale products with excellent batch consistency, low impurity content, no solvent residue and no microbial contamination, fully meeting the needs of pharmaceutical R&D, health product production, cosmetic formulations and functional food applications.

3. Pharmacological Activities and Functional Benefits

Ginsenoside CK is a multi‑target, multi‑pathway, high‑safety natural active compound. Modern pharmacological studies have confirmed its extensive and clear biological activities:

① Anti-Tumor Activity

Ginsenoside CK inhibits tumor cell proliferation, induces apoptosis, suppresses invasion and metastasis, and reverses drug resistance in tumor cells. Studies show it acts selectively with low toxicity to normal cells, making it a promising natural anti-tumor ingredient.

② Anti-Inflammatory and Tissue Protection

It inhibits inflammatory mediators and regulates inflammatory pathways, significantly reducing acute and chronic inflammation. It protects the liver, kidney, nerves and cardiovascular system by reducing oxidative stress and cell apoptosis.

③ Liver Protection and Metabolic Regulation

Ginsenoside CK improves liver function, reduces liver injury and promotes hepatocyte repair. It also regulates glucose and lipid metabolism, promotes insulin secretion, enhances insulin sensitivity and helps maintain metabolic balance.

④ Neuroprotection and Cognitive Improvement

It can cross the blood‑brain barrier to protect neurons, reduce neuroinflammation and improve cerebral microcirculation. It helps maintain nervous system health and delays cognitive decline.

⑤ Immune System Regulation

It enhances the activity of macrophages and lymphocytes, improves non‑specific immunity, relieves fatigue and improves physical fitness, reflecting the traditional “strengthening the body resistance” effect in modern science.

⑥ Anti-Allergy Effect

It inhibits histamine release and allergic reactions, relieves skin redness, itching and sensitivity, making it suitable for sensitive skin care products.

⑦ Antioxidation and Anti-Aging

It scavenges free radicals, reduces lipid peroxidation, protects collagen, reduces pigmentation and wrinkles, and delays skin aging — making it an ideal raw material for high‑end anti‑aging and whitening cosmetics.

4. Application Fields

① Pharmaceutical and Health Care Products

• Anti‑fatigue, anti‑aging and immune‑enhancing supplements

• Liver protection, metabolic regulation and sleep improvement products

• Innovative drug R&D for anti‑tumor, anti‑inflammatory and neuroprotection

• Suitable for sub‑health, post‑operation recovery and elderly healthcare

② Cosmetics and Personal Care

• Skin brightening, anti‑spot and melanin inhibition

• Anti‑wrinkle, firming and elasticity improvement

• Soothing sensitivity and repairing skin barrier

• Core active ingredient for serums, creams, masks and essences

③ Functional Foods and Dietary Supplements

• Solid drinks, oral liquids, tablets and capsules

• Sports nutrition and physical recovery products

• Formulas for immune health and metabolic support

5. Core Product Advantages

1. Direct active form with higher bioavailabilityAs the final metabolite of ginseng, Ginsenoside CK is directly absorbed and works efficiently without secondary conversion.

2. Multi-target effects for wide applicationsCovers anti‑tumor, anti‑inflammatory, liver protection, neuroprotection, immunity, anti‑aging and skin whitening.

3. High purity, low toxicity and high safetyNatural source, mild and non‑irritating, suitable for long‑term use.

4. Stable large‑scale productionFrom lab R&D to industrial manufacturing, with consistent batch quality and stable long‑term supply.

5. Highly customizableSupports various purity levels, particle sizes, solubility and packaging requirements.

6. Storage and Handling Recommendations

• Storage: Sealed, kept away from light, stored in cool and dry conditions

• Avoid: Mixing with strong acids, alkalis or oxidizing agents

• Shelf Life: 24 months under proper storage

• Applications: Pharmaceutical intermediates, health care raw materials, cosmetic active ingredients, functional food additives

7. Summary

Ginsenoside CK is one of the most active, widely applicable and highly valuable components in rare ginsenosides, representing an important direction in modern natural medicine and health raw materials. With advanced purification technology, strict quality control, large‑scale production capacity and one‑stop CDMO/CMO services, Shaanxi Cuikang Pharmaceutical Technology Co., Ltd. provides high‑quality Ginsenoside CK for global customers, supporting innovation in medicine, health products and cosmetics. We are your reliable long‑term partner.