Diosgenin（512-04-9）

1. Product Basic Information

Product Name: DiosgeninCAS Number: 512-04-9Molecular Formula: C₂₇H₄₂O₃Molecular Weight: 414.63Appearance: White to off-white crystalline powder, odorless, tastelessSolubility: Soluble in methanol, ethanol, acetone, ethyl acetate; almost insoluble in waterMelting Point: 204–207℃Purity: 95%, 98%, customizableSource: Extracted and purified from Dioscorea zingiberensis, Dioscorea nipponica and other Dioscoreaceae plants

Diosgenin is a natural steroidal sapogenin and the most important starting material for steroidal hormone drugs in the global pharmaceutical industry, known as “medical gold”. It is the key precursor for synthesizing hundreds of steroidal hormones including progesterone, hydrocortisone, dexamethasone, estradiol and testosterone. It is widely used in anti-inflammatory, anti-allergic, contraceptive, endocrine regulation and anti-tumor fields, and also has high application value in health products, cosmetics and functional foods.

Shaanxi Cuikang Pharmaceutical Technology Co., Ltd. provides high-purity, high-quality and stable diosgenin for global customers based on our natural product separation platform, UPLC‑Q‑TOF high‑resolution mass spectrometry and industrial production lines, supporting scalable supply from 100g to tons.

2. Production Process & Quality Advantages

Our diosgenin is produced through plant extraction → enzymatic hydrolysis → chromatographic separation → crystallization purification, maximizing structural integrity, reducing impurities and ensuring high purity and stability.

1. High-Quality Raw MaterialsSelected diosgenin-rich plants with strict control of heavy metals and pesticides.

2. Green Extraction TechnologyEnvironmentally friendly solvents and mild conditions avoid damage from high temperature and strong acid.

3. High-Precision PurificationChromatographic technology removes impurities, polysaccharides and pigments to ensure high purity and good crystal form.

4. Strict Quality ControlFull testing including appearance, purity, melting point, loss on drying, residue, heavy metals, microorganisms and solvent residues, complying with USP, EP and CP standards.

5. Stable Large-Scale ProductionOne-stop service from lab to industrial production with consistent batch quality.

6. Full TraceabilityComplete quality records, COA, HPLC reports and technical documents are available for audit.

3. Pharmacological Activities & Functions

① Key Precursor for Steroidal Hormone Drugs

Diosgenin is the foundation of the global steroidal drug industry. It can be modified to synthesize more than 400 drugs, including glucocorticoids, sex hormones, progestogens, for anti-inflammatory, anti-allergic, contraceptive and endocrine therapies.

② Lipid Regulation & Cardiovascular Protection

Lowers cholesterol and triglycerides, inhibits lipid peroxidation, protects vascular endothelium and prevents atherosclerosis.

③ Anti-Inflammatory, Antioxidant & Immune Regulation

Inhibits inflammatory factors, scavenges free radicals and enhances immune function.

④ Anti-Tumor Activity

Inhibits proliferation and induces apoptosis in various cancer cells, showing potential against liver, lung, breast and gastric cancers.

⑤ Blood Sugar & Liver Protection

Improves insulin resistance, lowers blood glucose and protects liver cells from damage.

⑥ Neuroprotection

Protects neurons, improves cerebral microcirculation and supports cognitive health.

⑦ Skin Care Benefits

Antioxidant, anti‑inflammatory, melanin‑inhibiting and anti‑aging properties for cosmetics.

4. Application Fields

① Pharmaceutical Industry (Core Use)

Starting material for steroidal hormones:

• Glucocorticoids: hydrocortisone, dexamethasone, prednisone

• Sex hormones: estradiol, testosterone

• Progestogens: progesterone

• Anti-inflammatory, anti-allergic, contraceptive drugs

② Health Products & Functional Foods

Lipid-lowering, cardiovascular protection, immunity enhancement, anti-aging supplements.

③ Cosmetics

Whitening, anti-aging, soothing and repairing active ingredients.

④ Veterinary Medicine

Steroidal hormones for animal growth and reproduction.

5. Core Product Advantages

1. Irreplaceable raw material for steroidal drugsUsed in >90% of global steroidal hormone production.

2. Natural source, high safetyPlant-derived, low impurity, non-toxic, suitable for pharma, food and cosmetics.

3. High purity, stability and crystal formPurity up to 98%, easy for storage, transport and synthesis.

4. Stable industrial supplyLarge-scale production ensures long-term supply at competitive prices.

5. Custom CDMO/CMO servicesCustom purity, packaging and technical support available.

6. Storage & Handling

• Storage: Sealed, dry, cool and away from light

• Avoid: Heat, moisture, strong acids, alkalis and oxidants

• Shelf Life: 24 months under proper storage

• Applications: Pharmaceutical intermediates, health raw materials, cosmetic ingredients, veterinary raw materials

7. Summary

Diosgenin is the most critical and irreplaceable starting material for global steroidal hormone drugs, with broad applications in medicine, health care, cosmetics and veterinary fields.

With advanced purification technology, strict quality control, large-scale production and professional CDMO/CMO services, Shaanxi Cuikang Pharma provides high-purity diosgenin to global partners. We adhere to “Reputation First, Quality Supreme, Win-Win Cooperation” and strive to be your most reliable long-term supplier.