GinsenosideRh1(CAS:63223-86-9)

Ginsenoside Rh1 (CAS: 63223-86-9), with molecular formula C₃₆H₆₂O₉ and molecular weight of 638.87, is a precious protopanaxatriol-type rare ginsenoside, mainly enriched during the processing of red ginseng. It has an extremely low content in raw ginseng and is largely generated after high-temperature steaming and thermal transformation. Compared with conventional ginsenosides, Ginsenoside Rh1 has smaller molecular weight, excellent skin permeability and low irritation, featuring outstanding affinity and biocompatibility. With unique skin care activity and stable physicochemical properties, it is widely used in cosmetics, liver protection, biomedicine and scientific research, serving as a high-end saponin monomer suitable for the beauty industry.

In terms of physical and chemical properties, Ginsenoside Rh1 appears as white crystalline powder with slight bitter taste and stable performance. It is easily soluble in organic solvents such as methanol and ethanol, and slightly soluble in water, compatible with alcohol-soluble and mild water-based skin care formulas. It has stable molecular structure and good acid and alkali resistance, not easy to deteriorate under sealed storage. However, long-term exposure to strong light and high humidity may cause moisture absorption and oxidation. It shall be stored in sealed, light-proof, cool and dry environment away from strong oxidants to maintain stable purity and biological activity.

In industrial production, Ginsenoside Rh1 is prepared from high-quality red ginseng through low-temperature extraction and multi-stage purification. The production procedures include raw material screening, cleaning, steaming transformation, crushing, alcohol extraction, vacuum concentration, macroporous resin impurity removal, HPLC refining, recrystallization and vacuum drying. Adopting pure physical purification without harmful residues, the process effectively removes polysaccharides and impurities. Industrial refined Ginsenoside Rh1 can reach a purity of more than 98%, meeting high-standard requirements for cosmetics, pharmaceuticals and scientific research.

Ginsenoside Rh1 has mild and diverse biological activities, mainly including skin repair, anti-inflammation, anti-oxidation and liver protection. In skin care, it improves skin microcirculation, scavenges epidermal free radicals, relieves redness and sensitivity, and repairs damaged skin barrier with obvious anti-aging and brightening effects. It inhibits the secretion of inflammatory factors, reduces oxidative damage and delays cell aging. For liver protection, it repairs hepatocytes and reduces metabolic toxin damage to the liver. With low irritation and high compatibility, it has high tolerance for human body and skin.

Ginsenoside Rh1 is positioned as a high-end fine raw material with strong industrial applicability. In the cosmetic industry, it is a core active ingredient for high-end anti-aging and repairing skincare products to improve dullness and skin aging. In the pharmaceutical field, it acts as a pharmaceutical intermediate for liver-protective and anti-inflammatory drugs. In health products, it is compounded with other saponins to make mild conditioning supplements. In scientific research, it is widely used as a standard reference substance for saponin detection and pharmacological experiments.

With the popularity of natural skin care concepts, mild plant active raw materials have become the mainstream of the market. Benefiting from low irritation, high permeability and excellent skin care efficacy, Ginsenoside Rh1 has achieved steady growth in market demand. In the future, with optimized purification technology and reduced production cost, its application scope in cosmetics and medicine will be further expanded. With pure quality, natural source and diverse mild activities, Ginsenoside Rh1 will continue to develop in beauty and biomedicine industries, becoming a benchmark product with high commercial value among protopanaxatriol rare ginsenosides.