Neodiosmin(CAS:38665-01-9)

Neodiosmin (CAS: 38665-01-9), with molecular formula C₂₈H₃₂O₁₅ and molecular weight of 608.54, is a precious natural flavonoid active compound mainly extracted from immature fruits of rutaceae plants such as sour orange and bitter orange. As an isomer of diosmin, Neodiosmin has a unique molecular structure and biological characteristics. It not only retains the excellent antioxidant and anti-inflammatory activities of flavonoids, but also has a rare bitterness inhibitory function in the industry. It is a high-end flavonoid raw material with both functionality and uniqueness in the fields of food modification and vascular maintenance. With the advantages of non-toxicity, stable properties and diverse efficacy, it is widely used in food additives, pharmaceutical intermediates, dietary supplements and cosmetics.

In terms of physical and chemical properties, Neodiosmin is white crystalline powder with pure color and no peculiar smell under normal temperature, featuring stable physical and chemical properties. It is easily soluble in organic solvents such as methanol and ethanol, slightly soluble in hot water, and insoluble in cold water, which is suitable for a variety of industrial production formulas. It has a moderate melting point and a chemically stable structure. Although it can be stored stably in dry environment at room temperature, it is prone to oxidative discoloration under strong light, high temperature and humid conditions. Therefore, it needs to be stored in sealed, light-proof, low-temperature and dry environment away from strong oxidants to maintain high purity and activity.

In terms of production technology, Neodiosmin is prepared from natural bitter orange and citrus immature fruits through green plant extraction process. The production process includes raw material screening, cleaning and crushing, ethanol extraction, chromatographic separation, refining and purification, recrystallization and low-temperature drying. With macroporous resin adsorption and high-efficiency liquid-phase purification technology, isomers are accurately separated to remove impurities. The industrial purification process can stably produce high-purity Neodiosmin with purity over 98%, which meets food-grade and pharmaceutical-grade standards without harmful residues, suitable for large-scale industrial production and laboratory research.

Neodiosmin has multiple excellent biological activities, including vascular maintenance, anti-oxidation and anti-inflammation. In terms of vascular care, it can strengthen capillary toughness, reduce vascular permeability, improve microcirculation disorders, and relieve venous congestion and limb soreness. As for anti-oxidation, it can scavenge free radicals and reduce oxidative damage to cells. Its anti-inflammatory performance inhibits the release of inflammatory factors and relieves mild inflammation. Different from ordinary flavonoids, its most unique advantage is natural bitterness inhibition, which can shield bitter odor in food and act as a natural food flavor modifier.

Neodiosmin has a wide range of application scenarios relying on its unique advantages. In the food industry, it is used as a natural bitterness inhibitor to improve the taste of functional beverages and bitter health food. In the pharmaceutical field, it serves as a pharmaceutical intermediate for developing microcirculation-improving drugs. In the health product industry, it is compounded with other flavonoids to make dietary supplements for vascular care. In cosmetics, it is added into skin care products to relieve sensitivity, resist oxidation and improve dull skin tone.

With the rapid development of natural additives and functional raw materials, pure natural raw materials have become the mainstream of the market. Due to its unique bitterness inhibition and mild maintenance characteristics, Neodiosmin has become a dual-purpose raw material for food flavoring and vascular care. In the future, with the continuous optimization of extraction technology, the production cost will be further reduced, and its application scope will be expanded to fine chemical and biomedical fields. With stable quality and unique functionality, Neodiosmin will occupy a stable position in the high-end natural flavonoid raw material market.